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Brexanolone (Zulresso).

A prescription medication used to treat postpartum depression (PPD), a condition that affects women after giving birth.

  • Common Brand Name(s): Brexanolone
  • Common Generic Name(s): Zulresso
  • Pronunciation:(brex ANN oh lone)

Whats is Brexanolone?

A treatment for moderate-to-severe postpartum depression (PPD) that is administered through intravenous injection (IV). It helps by balancing substances in your brain to help regulate emotions.

medication to treat post partum depression

Zulresso for intravenous use – 100 mg/20 mL

Zulresso (brexanolone) is a gamma-aminobutyric acid A (GABAA) receptor positive allosteric modulator indicated for the treatment of postpartum depression (PPD).

Conditions Treated with Brexanolone (Zulresso)

Postpartum Depression

Side Effects

Buprenorphine can cause a range of side effects, some common and others more serious. It’s important to be aware of these potential effects and to discuss any concerns with your doctor.

Common Side Effects:

  • dizziness or lightheadedness
  • drowsiness
  • fainting
  • feeling of constant movement of self or surroundings
  • relaxed and calm feeling
  • sensation of spinning
  • sleepiness or unusual drowsiness

Less Common Side Effects:

  • fast, pounding, or irregular heartbeat or pulse
  • loss of consciousness
  • acid or sour stomach
  • belching
  • diarrhea
  • feeling of warmth
  • heartburn
  • indigestion
  • mouth or throat pain
  • redness of the face, neck, arms, and occasionally, upper chest
  • stomach discomfort, upset, or pain

Serious Side Effects:

Get emergency help immediately if any of the following symptoms of overdose occur while taking brexanolone:

Symptom of overdose

  • prolonged drowsiness

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