Acamprosate (Campral®).

Brand Name: Acamprosate

Generic Name: Campral®

Physical Description: Enteric-coated white, round, biconvex tablets, identified with “333” (generic) or “435” (brand name) debossed on one side.



This is no black box warning for Acamprosate.

What is Acamprosate?

Acamprosate (Campral®) is a pharmaceutical medication FDA approved to treat alcohol use disorder.

Side Effects

The most common side effect of Acamprosate is Diarrhea.

Rare and serious side effects include:

  • Chest pain
  • Increased blood pressure
  • Increased heart rate
  • Swelling
  • Nausea
  • Appetite changes
  • Internal gas
  • Weakness
  • Pain
  • Anxiety
  • Depression
  • Dizziness
  • Dry mouth
  • Headaches
  • Insomnia
  • Weight gain
  • Tingling sensations
  • Itching
  • Sweating
  • Vision changes
  • Suicidal thoughts
    If you experience any of these symptoms, it is advised to contact your care provider as soon as possible.

FDA Approved to Treat

Alcohol Use Disorder


Acamprosate recommended dosage is 666 mg (two tablets) taken three times a day.

For individuals who have renal impairment, starting with one 333mg tablet 3-times daily is advised.

Missed Dose

If you miss a dose, take the medicine as soon as possible. If it is almost time for your next dose, skip the missed dose and do not take two doses at one time.


If any of the following factors are found to be true for a patient, it is not advised to prescribe acamprosate. In these instances, the risks may outweigh the benefits of utilizing this medication.

  • hypersensitivity to acamprosate calcium or any of its components
  • severe renal impairment

Medication Interactions

There are no significant known drug interactions with acamprosate. Still, it is advised to disclose all medications you are taking with your doctor.

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